Ruth Anne Eatock, Ph.D.
Eaton-Peabody Laboratory, Massachussetts Eye and Ear Infirmary
eatock@meei.harvard.edu
Education:
McGill University, B.S. in Neurobiology
McGill University, M.S. in Biology
California Institute of Technology, Ph.D. in Biology
Publications:
1. Eatock RA,
2. Eatock RA,
3. Eatock RA, Corey DP, Hudspeth AJ. Adaptation of mechanoelectrical transduction in hair cells of the bullfrog's sacculus. J Neurosci. 1987;7(9):2821-36.
4. Smith-Maxwell CJ, Eatock RA, Begenisich T. Induction of K-channel expression in a neuroblastoma cell line. J Neurobiol. 1991;22(4):327-41.
5. Eatock RA, Weiss TF, Otto KL. Dependence of discharge rate on sound pressure level in cochlear nerve fibers of the alligator lizard: implications for cochlear mechanisms. J Neurophysiol. 1991;65 (6):1580-97.
6. Eatock RA, Hutzler MJ. Ionic currents of mammalian vestibular hair cells. Ann N Y Acad Sci. 1992;656:58-74.
7. Nealey T, Spires S, Eatock RA, Begenisich T. Potassium channels in squid neuron cell bodies: comparison to axonal channels. J Membr Biol. 1993;132(1):13-25.
8. Eatock RA, Saeki M, Hutzler MJ. Electrical resonance of isolated hair cells does not account for acoustic tuning in the free-standing region of the alligator lizard's cochlea. J Neurosci. 1993;13 (4):1767-83.
9. Holt JR, Eatock RA. Inwardly rectifying currents of saccular hair cells from the leopard frog. J Neurophysiol. 1995;73(4):1484-502.
10. Rüsch A, Eatock RA. Voltage responses of mouse utricular hair cells to injected currents. Ann NY Acad Sci. 1996;781:71-84.
11. Rüsch A, Eatock RA. A delayed rectifier conductance in type I hair cells of the mouse utricle. J Neurophysiol. 1996;76(2):995-1004.
12. Eatock RA, Rüsch A. Developmental changes in the physiology of hair cells. Semin Cell Dev Biol. 1997;8(3):265-275.
13. Holt JR, Corey DP, Eatock RA. Mechanoelectrical transduction and adaptation in hair cells of the mouse utricle, a low-frequency vestibular organ. J Neurosci. 1997;17(22):8739-48.
14. Oghalai JS, Holt JR, Nakagawa T, Jung TM, Coker NJ, Jenkins HA, Eatock RA, Brownell WE. Ionic currents and electromotility in inner ear hair cells from humans. J Neurophysiol. 1998;79 (4):2235-9.
15. Eatock RA, Rüsch A, Lysakowski A, Saeki M. Hair cells in mammalian utricles. Otolaryngol Head Neck Surg. 1998;119(3):172-81.
16. Rüsch A, Lysakowski A, Eatock RA. Postnatal development of type I and type II hair cells in the mouse utricle: acquisition of voltage-gated conductances and differentiated morphology. J Neurosci. 1998;18(18):7487-501.
17. Holt JR, Vollrath MA, Eatock RA. Stimulus processing by type II hair cells in the mouse utricle. Ann N Y Acad Sci. 1999;871:15-26.
18. Bermingham NA, Hassan BA, Price SD, Vollrath MA, Ben-Arie N, Eatock RA, Bellen HJ, Lysakowski A, Zoghbi HY. Math1: an essential gene for the generation of inner ear hair cells. Science. 1999;284(5421):1837-41.
19. Eatock RA. Adaptation in hair cells. Annu Rev Neurosci. 2000;23:285-314.
20. Oghalai JS, Holt JR, Nakagawa T, Jung TM, Coker NJ, Jenkins HA, Eatock RA, Brownell WE. Harvesting human hair cells. Ann Otol Rhinol Laryngol. 2000;109(1):9-16.
21. Chen JW, Eatock RA. Major potassium conductance in type I hair cells from rat semicircularcanals: characterization and modulation by nitric oxide. J Neurophysiol. 2000;84(1):139-51.
22. Liu M, Pereira FA,
23. Eatock RA, Hurley KM, Vollrath MA. Mechanoelectrical and voltage-gated ion channels in mammalian vestibular hair cells. Audiol Neurootol. 2002;7(1):31-5.
24. Brichta AM, Aubert A, Eatock RA, Goldberg JM. Regional analysis of whole cell currents from hair cells of the turtle posterior crista. J Neurophysiol. 2002;88(6):3259-78.
25. Bao H, Wong WH, Goldberg JM, Eatock RA. Voltage-gated calcium channel currents in type I and type II hair cells isolated from the rat crista. J Neurophysiol. 2003;90(1):155-64.
26. Vollrath MA, Eatock RA. Time course and extent of mechanotransducer adaptation in mouse utricular hair cells: comparison with frog saccular hair cells. J Neurophysiol. 2003;90(4):2676-89.
27. Wong WH, Hurley KM, Eatock RA. Differences between the negatively activating potassium conductances of Mammalian cochlear and vestibular hair cells. J Assoc Res Otolaryngol. 2004;5 (3):270-84.
28. Spector AA, Popel AS, Eatock RA, Brownell WE. Mechanosensitive channels in the lateral wall can enhance the cochlear outer hair cell frequency response. Ann Biomed
29. Hurley KM, Gaboyard S, Zhong M, Price SD, Wooltorton JRA, Lysakowski A, Eatock RA. M-like K+ currents in type I hair cells and calyx afferent endings of the developing rat utricle. J Neurosci. 2006; 26(40):10253-10269.
30. Wooltorton JRA, Gaboyard S, Hurley KM, Price SD, Bao H, Garcia JL, Lysakowski A, Eatock RA (2007) Developmental changes in two voltage-dependent sodium currents in utricular hair cells. J Neurophysiol 97:1684-1704
Reviews, Chapters, and Editorials
1. Eatock RA (1995) Procesamiento de los estimulos en las celulas pilosas
2. Rüsch A, Eatock RA (1997) Sodium currents in hair cells of the mouse utricle. In: Diversity in Auditory Mechanics (ER Lewis, GR Long, RF Lyon, CR Steele, PM Narins, E Poinar, eds.) World Scientific Publishing Co. Pte. Ltd.,
3. Eatock RA. Auditory physiology: listening with K+ channels. Curr Biol. 2003;13(19):R767-9.
4. Eatock RA, Hurley KM. Functional development of hair cells. Curr Top Dev Biol. 2003;57:389-448.
5. Eatock RA (2006) Vertebrate hair cells: Modern and historic perspectives. In: Vertebrate Hair Cells (Eatock, Fay, Popper, eds.) Springer:
6. Eatock RA, Lysakowski A (2006) Mammalian vestibular hair cells. In: Vertebrate Hair Cells (Eatock, Fay, Popper, eds.) Springer:
7. Wooltorton JRA, Hurley KM, Bao H, Eatock RA (in press) Voltage-dependent sodium channels in hair cells of the inner ear, in: Topics in Integrative Neuroscience: From Cells to Cognition, eds. Pomerantz, J.R. &. Crair, M.C.,