3-D Virtual Model of the Round Window and Related Cochlear Anatomy

We have developed a 3-D virtual model of the anatomy of the round window membrane and adjacent cochlear structures in the human.  Knowledge of the spatial relationship of these structures has implications for cochlear implantation, wherein preservation of residual hearing is an important aim in some cases.  Archival, 20 micron, celloidin embedded sections from a 14-year old male were used.  Each and every section through the round window was stained, digitized and imported into a 3-D software program (Amira, version 3.1).  A total of 201 number of sections were used to generate the model.  The resulting 3-D model is a surface rendering of structures of interest including the round window, basilar membrane, osseous spiral lamina, scala media, spiral ligament, cochlear aqueduct, inferior cochlear vein and related venous structures, scala vestibuli, scala tympani and ductus reuniens. 

The model was developed by Haobing Wang, Clarinda Northrop, Barbara Burgess, Saumil Merchant, M.D., and Joseph B. Nadol, Jr., M.D.  Supported by a Core grant from the NIDCD (P30 DC05209).



Screen shots of 3-D model of Round Window
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