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Publications of the EPL Neural Coding Group

Selected papers and recent abstracts are organized by research area and available as Adobe PDF files.

Research Areas:

bulletNeural coding of pitch and music
bulletNeural correlates of binaural and spatial hearing
bulletPhysiological studies of cochlear implants
bulletFunctional organization of the inferior colliculus
bulletPerception and neural coding of temporal envelope
bulletNeural representation of speech
bulletComputational models of auditory neurons
bulletPhysiological basis of masking and frequency selectivity

Neural mechanisms of binaural and spatial hearing

Journal Publications

  1. Devore S, Ihlefeld A, Hancock KE, Shinn-Cunningham B,  Delgutte B.  Accurate sound localization in reverberant environments is mediated by robust encoding of spatial cues in the auditory midbrain.  Neuron 2009; 62: 123-134.  PDF  Commentary by Terry Takahashi

  2. Dreyer A, Delgutte B.  Phase locking of auditory-nerve fibers to the envelopes of high-frequency sounds: Implications for sound localization.  J. Neurophysiol. 2006; 96:2327-2341.  PDF

  3. Lane CC, Delgutte B.   Neural correlates and mechanisms of spatial release from masking: Single-unit and population responses in the inferior colliculus.  J Neurophysiol. 2005; 94: 1180-1198.  PDF

  4. Hancock KE, Delgutte B.  A physiologically-based model of interaural time difference discrimination.  J Neurosci. 2004; 24: 7110-7117.  PDF

  5. Litovsky RY, Delgutte B.  Neural correlates of the precedence effect in the inferior colliculus:  Effect of localization cues.  J. Neurophysiol. 2002; 87:976-994.  PDF  Zip Archive of Matlab Data

  6. Delgutte B, Joris PX, Litovsky RY, Yin TCT.  Receptive fields and binaural interactions for virtual space stimuli in the cat inferior colliculus.  J. Neurophysiol. 1999; 81:2833-2851.  PDF  Zip Archive of Matlab Data

Conference Proceedings

  1.  Devore S., Schwartz A. and Delgutte B.  Effect of reverberation on directional sensitivity of auditory neurons: Central and peripheral factors. In Advances in Auditory Research: Physiology, Psychophysics and Models, edited by E. Lopez-Poveda and R. Meddis, Springer, in press.  PDF

  2. Devore S, Ihlefeld B,  Shinn-Cunningham BG, Delgutte B.  Neural and behavioral sensitivities to azimuth degrade with distance in reverberant environments.  In Hearing – From Basic Research to Applications, Kollmeier B, Klump G, Hohmann V, Langemann U, Mauermann M, Uppenkamp S, Verhey J (eds), Springer: New York, 2007: 505-516.  PDF

  3. Hancock KE.  A physiologically-based rate code for interaural time differences (ITD) predicts bandwidth-dependent lateralization.  In Hearing – From Basic Research to Applications, Kollmeier B, Klump G, Hohmann V, Langemann U, Mauermann M, Uppenkamp S, Verhey J (eds), Springer: New York, 2007: 389-398.  PDF

  4. Lane CC, Kopco N, Delgutte B, Shinn-Cunningham BG, Colburn HS.   A cat's cocktail party: Psychophysical, neurophysiological and computational studies of spatial release from masking.  In: Auditory signal processing: Physiology, psychoacoustics, and models, Pressnitzer D, de Cheveigne A, McAdams S, Collet L (eds).  Springer, 2005: 405-413.  PDF

  5. Litovsky RY, Lane CC, Atencio C, Delgutte B.  Physiological measures of the precedence effect and spatial release from masking in the cat inferior colliculus. In Physiological and Psychophysical Bases of Auditory Function, DJ Breebaart, AJM Houtsma, A Kohlrausch, VF Prijs, and R Schoonhoven (eds).  Maastricht: Shaker, 2001: 221-228.  PDF

Recent Abstracts

  1. Schwartz  A., Devore S, Delgutte B.  Effect of reverberation of the directional sensitivity of auditory neurons: Peripheral factors.  Abstr. Assoc. Res. Otolaryngol. 32:622, 2009.

  2. Devore S, Delgutte B.  Effect of reverberation on neuronal sensitivity to fine time structure and envelope ITD in the inferior colliculus of awake rabbit.  Abstr. Assoc. Res. Otolaryngol. 31:868, 2008.  PDF

  3. Hancock KE.  A physiologically-based population rate code for interaural time differences (ITDs) predicts bandwidth-dependent lateralization.  Abstr. Assoc. Res. Otolaryngol. 30:1062, 2007. 

  4. Dreyer A, Oxenham AJ, Delgutte B.  Predicting lateralization performance at high frequencies from auditory-nerve spike timing.  Abstr. Assoc. Res. Otolaryngol. 28:976, 2005.  PDF

  5. Hancock KE, Delgutte B.  Neural correlates of the Huggins dichotic pitch.  Abstr. Assoc. Res. Otolaryngol. 25:153, 2002.  PDF

Theses

  1. Devore S.  Neural correlates and mechanisms of sound localization in everyday reverberant settings.  Doctoral Dissertation, Harvard-MIT Division of Health Sciences and Technology, 2009.  PDF
  2. Dreyer A. Predicting lateralization at high frequencies from auditory-nerve spike timing.  MEng Thesis, Department of Electrical Engineering and Computer Science, MIT, 2005.  PDF
  3. Lane CC.  Signal detection in the auditory midbrain: Neural correlates and mechanisms of spatial release from masking.  Doctoral Dissertation, Harvard-MIT Division of Health Sciences and Technology, 2003.  PDF

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Physiological studies of cochlear implants

Journal Publications

  1. Smith ZM, Delgutte B.  Sensitivity of inferior colliculus neurons to interaural time differences in the envelope versus the fine structure with bilateral cochlear implants.  J Neurophysiol. 2008; 99:2390-2407.  PDF

  2. Smith ZM, Delgutte B.  Sensitivity to interaural time differences in the inferior colliculus with bilateral cochlear implants.  J. Neurosci. 2007; 27:6740-6750.  PDF

  3. Smith ZM, Delgutte B.  Using evoked potentials to match interaural electrode pairs with bilateral cochlear implants.  J. Assos. Res. Otolaryngol. 2007; 8:134-151.  PDF

  4. Litvak LM, Smith ZM, Delgutte B, Eddington DK.  Desynchronization of electrically-evoked auditory-nerve activity by high-frequency pulse trains of long duration.  J. Acoust. Soc. Am. 2003; 114:2066-2078.  PDF

  5. Litvak LM, Delgutte B, Eddington DK.  Improved temporal coding of sinusoids in electric stimulation of the auditory nerve using desynchronizing pulse trains.  J. Acoust. Soc. Am. 2003; 114:2079-2098.  PDF

  6. Litvak LM, Delgutte B, Eddington DK.  Improved neural representation of vowels in electric stimulation using desynchronizing pulse trains.  J. Acoust. Soc. Am. 2003; 114:2099-2111.  PDF

  7. Litvak, LM, Delgutte, B, Eddington DK.  Auditory nerve fiber responses to electric stimulation: Modulated and unmodulated pulse trains.  J. Acoust. Soc. Am. 2001; 110:368-379.  PDF

  8. Dynes SBC, Delgutte B.  Phase locking of auditory-nerve discharges to sinusoidal electric stimulation of the cochlea.  Hearing Res. 1992; 58: 79-90.  PDF

Conference Proceedings

  1. Goupell M., Hancock K., Majdak M., Laback B. and Delgutte B.  Binaurally-coherent jitter improves neural and perceptual ITD sensitivity in normal and electric hearing.  In Advances in Auditory Research: Physiology, Psychophysics and Models, edited by E. Lopez-Poveda and R. Meddis, Springer, in press.  PDF

Recent Abstracts

  1.  Hancock KE, Delgutte B.  ITD coding with bilateral cochlear implants: Effects of congenital deafness and binaurally-coherent jitter.  Abstr. Assoc. Res. Otolaryngol. 32:468, 2009.

  2. Hancock KE, Noel VA.  A physiologically-based Model of ITD discrimination in a bilateral cochlear implant subject.   Abstr. Assoc. Res. Otolaryngol. 31:883, 2008.  PDF

Thesis

  1. Smith ZM.  Binaural interactions in the auditory midbrain with bilateral electric stimulation of the cochlea.  Doctoral Dissertation, Harvard-MIT Division of Health Sciences and Technology, 2006.  PDF

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Neural correlates of pitch and music

Journal Publications

  1. Larsen E, Cedolin L, Delgutte B.  Pitch representations in the auditory nerve: Concurrent complex tones.  J. Neurophysiol. 2008; 100: 1301-1319.  PDF

  2. Cedolin L, Delgutte B.  Pitch of complex tones: Rate-place and interspike-interval representations in the auditory nerve. J. Neurophysiol. 2005; 94: 347–362.  PDF

  3. McKinney MF, Delgutte B.  A possible neurophysiological basis of the octave enlargement effect.  J. Acoust. Soc. Am. 1999; 106:2619-2692.  PDF  Zip Archive of Matlab Data

  4. Cariani PA, Delgutte B.  Neural correlates of the pitch of complex tones. I. Pitch and pitch salience. J. Neurophysiol. 1996; 76:1698-1716.  PDF

  5. Cariani PA, Delgutte B.  Neural correlates of the pitch of complex tones. II. Pitch shift, pitch ambiguity, phase invariance, pitch circularity, rate pitch and the dominance region for pitch.  J. Neurophysiol. 1996; 76:1717-1734.  PDF

Conference Proceedings

  1. Cedolin L, Delgutte B.  Spatio-temporal representation of the pitch of complex tones in the auditory nerve. In Hearing – From Basic Research to Applications, Kollmeier B, Klump G, Hohmann V, Langemann U, Mauermann M, Uppenkamp S, Verhey J (eds), Springer Verlag: New York, pp. 61-70.  PDF

  2. Cedolin L, Delgutte B.  Representations of the pitch of complex tones in the auditory nerve.  In: Auditory signal processing: Physiology, psychoacoustics, and models, Pressnitzer D, de Cheveigne A, McAdams S, Collet L (eds).  Springer 2005: 107-116.   PDF

  3. McKinney MF, Tramo MJ, Delgutte B. Neural correlates of the dissonance of musical intervals in the inferior colliculus.  In Physiological and Psychophysical Bases of Auditory Function, DJ Breebaart, AJM Houtsma, A Kohlrausch, VF Prijs, and R Schoonhoven (eds).  Maastricht: Shaker, 2001: 83-89.  PDF

Recent Abstracts

  1. Wang GI, Delgutte B.  Spatio-temporal processing of auditory-nerve activity in the cochlear nucleus.  Abstr. Assoc. Res. Otolaryngol. 32:845, 2009.

  2. Wang GI, Delgutte B.  Spatio-temporal representation of the pitch of complex tones in the auditory nerve and cochlear nucleus.  Abstr. Assoc. Res. Otolaryngol. 31:823, 2008.  PDF

  3. Larsen E, Cedolin L, Delgutte B.  Coding of pitch in the auditory nerve: Two simultaneous complex tones.  Abstr. Assoc. Res. Otolaryngol. 28:1021, 2005.  PDF

  4. Cedolin L, Delgutte B.  Spatio-temporal representation of the pitch of complex tones in the auditory nerve.  Abstr. Assoc. Res. Otolaryngol. 28:1195, 2005.  PDF

Theses

  1. Cedolin L.  Neural representations of pitch: Role of peripheral frequency selectivity.  Doctoral Dissertation, Harvard-MIT Division of Health Sciences and Technology, 2006.  PDF

  2. McKinney MF.  Neural correlates of pitch and roughness: Towards the neural code for melody and harmony perception.  Doctoral Dissertation, Harvard-MIT Division of Health Sciences and Technology, 2001.  PDF

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Masking, frequency selectivity and intensity discrimination

Journal Publications and Review

  1. Wen B., Wang G.I., Dean I. and Delgutte B.  Dynamic range adaptation to sound level statistics in the auditory nerve,  J. Neurosci. 2009; 29: 13797–13808.  PDF

  2. Delgutte B.  Physiological models for basic auditory percepts.  In Auditory Computation, edited by HH Hawkins, TA McMullen, AN Popper, and RR Fay.  New York: Springer, 1996: 157-220.  PDF
  3. Delgutte B.  Physiological mechanisms of psychophysical masking:  Observations from auditory-nerve fibers.  J. Acoust. Soc. Am. 1990; 87:791-809.  PDF
  4. Delgutte B.  Two-tone rate suppression in auditory-nerve fibers: Dependence on suppressor frequency and level.  Hearing Res. 1990; 49: 225-246.  PDF

Conference Proceedings

  1. Delgutte B.  Physiological mechanisms of masking.  In: H Duifhuis, W Horst, and HP Wit, eds.  Basic Issues in Hearing. London: Academic, 1988: 204-214.  PDF
  2. Delgutte B.     Peripheral auditory processing of speech information: Implications from a physiological study of intensity discrimination.  In: M.E.H. Schouten, ed.  The Psychophysics of Speech Perception.  Dordrecht: Nijhof, 1987: 333-353.  PDF

Abstract

  1. Wen B., Wang G., Dean I., Delgutte B.  Rapid dynamic range adaptation in the auditory nerve.  Abstr. Assoc. Res. Otolaryngol. 32:621, 2009.  PDF
  2. Cedolin L, Delgutte B.  Frequency selectivity of auditory-nerve fibers studied with band-reject noise.  Abstr. Assoc. Res. Otolaryngol. 25:330, 2002.  PDF

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Perception and neural coding of temporal envelope and fine structure

Journal Publication

  1. Smith ZM, Oxenham AJ, Delgutte B.  Chimaeric sounds reveal dichotomies in auditory perception.  Nature 2002; 416:87-90.  PDF   Audio demonstration of auditory chimeras

Conference Proceeding

  1. Delgutte B, Hammond BM, Cariani PA.  Neural coding of the temporal envelope of speech: Relation to modulation transfer functions.  In Psychophysical and Physiological Advances in Hearing, AR Palmer, A Reese, AQ Summerfield, and R Meddis (eds).  London: Whurr, 1998: 595-603.  PDF

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Functional organization of the inferior colliculus

Journal Publication

  1. Seshagiri CV, Delgutte B.  Responses properties of neighboring neurons in auditory midbrain for pure tone stimulation: A tetrode study.  J. Neurophysiol. 2007; 98:2058-2073.  PDF

Thesis

  1. Seshagiri CV.  Response properties of neighboring neurons in the auditory midbrain.  Doctoral Dissertation, Harvard-MIT Division of Health Sciences and Technology, 2006.  PDF

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Mathematical models of auditory neurons

Journal Publications

  1. Kalluri S, Delgutte B.  Mathematical models of cochlear nucleus onset neurons.  I. Point neuron with many weak synaptic inputs.  J. Comput. Neurosci. 2003; 14:71-90.  PDF
  2. Kalluri S, Delgutte B.  Mathematical models of cochlear nucleus onset neurons.  II. Model with dynamic spike blocking state.  J. Comput. Neurosci. 2003; 14:91-110.  PDF

Conference Proceeding

  1. Kalluri S, Delgutte B.  Characteristics of cochlear nucleus onset units studied using a model.  In Computational Models of Auditory Function, SG Greenberg and ML Slaney (eds). Amsterdam: IOS Press, 2001; 29-44. PDF

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Neural representation of speech

Journal Publications and Review

  1. Delgutte B.  Auditory neural processing of speech.  In The Handbook of Phonetic Sciences, WJ Hardcastle and J Laver (eds).  Oxford: Blackwell, 1997; 507-538.  PDF

  2. Delgutte B, Kiang NYS.  Speech coding in the auditory nerve: I. Vowel-like sounds.  J. Acoust. Soc. Am. 1984; 75:866-878.  PDF

  3. Delgutte B.  Speech coding in the auditory nerve: II. Processing schemes for vowel-like sounds.  J. Acoust. Soc. Am. 1984; 75:879-886.  PDF

  4. Delgutte B, Kiang NYS.  Speech coding in the auditory nerve: III. Voiceless fricative consonants.  J. Acoust. Soc. Am. 1984; 75:887-896.  PDF

  5. Delgutte B, Kiang NYS.  Speech coding in the auditory nerve: IV. Sounds with consonant-like dynamic characteristics.  J. Acoust. Soc. Am. 1984; 75:897-907.  PDF

  6. Delgutte B, Kiang NYS.  Speech coding in the auditory-nerve: V. Vowels in background noise.  J. Acoust. Soc. Am. 1984; 75:908-918.  PDF

Conference Proceeding

  1. Hirahara T, Cariani PA, Delgutte B.  Representation of low-frequency formants in the auditory nerve. Proc. ESCA Workshop on the Auditory Basis of Speech Perception, Keele, UK, 1996; 83-86.  PDF

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